IFIH1 monoclonal antibody (M02), clone 3F6
产品名称： IFIH1 monoclonal antibody (M02), clone 3F6
英文名称： IFIH1 monoclonal antibody (M02), clone 3F6
产品编号： H00064135-M02
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant IFIH1.
- Immunogen:
- IFIH1 (NP_071451.2, 928 a.a. ~ 1023 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- HVNMTPEFKELYIVRENKALQKKCADYQINGEIICKCGQAWGTMMVHKGLDLPCLKIRNFVVVFKNNSTKKQYKKWVELPITFPNLDYSECCLFSD
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- MSDS:
Download
- Applications
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to IFIH1 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged IFIH1 is 3 ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 64135
- GeneBank Accession#:
- NM_022168
- Protein Accession#:
- NP_071451.2
- Gene Name:
- IFIH1
- Gene Alias:
- Hlcd,IDDM19,MDA-5,MDA5,MGC133047
- Gene Description:
- interferon induced with helicase C domain 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon (IFNB) and a protein kinase C-activating compound, mezerein (MEZ). Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. [provided by RefSeq
- Other Designations:
- DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide,helicard,melanoma differentiation associated protein-5
- Related Disease
- Addison Disease
- Arthritis, Rheumatoid
- Autoimmune Diseases
- Carcinoma
- Cardiovascular Diseases
- Celiac Disease
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Edema
- Encephalomyelitis, Autoimmune, Experimental
- Genetic Predisposition to Disease
- Graves Disease
- Graves Ophthalmopathy
- Hashimoto Disease
- IgA Deficiency
- Lupus Erythematosus, Systemic
- Multiple Sclerosis
- Multiple Sclerosis, Relapsing-Remitting
- Prostatic Neoplasms