CASP9 polyclonal antibody
产品名称： CASP9 polyclonal antibody
英文名称： CASP9 polyclonal antibody
产品编号： PAB9490
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CASP9.
- Immunogen:
- A synthetic peptide corresponding to residues surrounding amino acids 290 of human CASP9.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 46, 33-36, 20-25
- Reactivity:
- Bovine, Hamster, Human, Mouse, Pig, Rabbit, Rat
- Specificity:
- This antibody detects proform (~46 KDa), intermediate (~33-36 KDa), and the fully cleaved (~20-25 KDa) caspase-9.
- Form:
- Liquid
- Storage Buffer:
- In PBS, pH 7.2 (30% glycerol, 0.5 mg/mL BSA, 0.01% thimerosal)
- Storage Instruction:
- Store at -20°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (0.5-4 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- WY-14,643 induced cell proliferation and oxidative stress in mouse liver are independent of NADPH oxidase.
Woods CG, Burns AM, Bradford BU, Ross PK, Kosyk O, Swenberg JA, Cunningham ML, Rusyn I.Toxicol Sci. 2007 Aug;98(2):366-74. Epub 2007 May 5.
- 2.
- IMP dehydrogenase inhibitor mycophenolate mofetil induces caspase-dependent apoptosis and cell cycle inhibition in multiple myeloma cells.
Takebe N, Cheng X, Fandy TE, Srivastava RK, Wu S, Shankar S, Bauer K, Shaughnessy J, Tricot G.Mol Cancer Ther. 2006 Feb;5(2):457-66.
- 3.
- Mitochondria-associated apoptotic signalling in denervated rat skeletal muscle.
Siu PM, Alway SE.J Physiol. 2005 May 15;565(Pt 1):309-23. Epub 2005 Mar 17.
- Entrez GeneID:
- 842
- Gene Name:
- CASP9
- Gene Alias:
- APAF-3,APAF3,CASPASE-9c,ICE-LAP6,MCH6
- Gene Description:
- caspase 9, apoptosis-related cysteine peptidase
- Omim ID:
- 602234
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms. [provided by RefSeq
- Other Designations:
- ICE-like apoptotic protease 6,OTTHUMP00000002322,OTTHUMP00000002323,OTTHUMP00000044594,apoptotic protease MCH-6,apoptotic protease activating factor 3,caspase 9,caspase 9, apoptosis-related cysteine protease
- Interactome
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